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Rifampin and Isoniazid
What is it? Overview Usage Side Effects and Warnings
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Rifampin and Isoniazid Overview

Written by FoundHealth.

(rif AM pin & eye soe NYE a zid)

U.S. Brand Names

IsonaRif™; Rifamate®

Canadian Brand Names

Rifamate®

Mexican Brand Names

Rifinah

Pharmacologic Category

Antibiotic, Miscellaneous

What key warnings should I know about before taking this medicine?

• This medicine may cause hepatitis.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

Reasons not to take this medicine

• If you have an allergy to isoniazid, rifampin, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have liver disease.

• If you had liver damage while taking isoniazid in the past.

How does it work?

• Isoniazid and rifampin work to injure the bacteria and fight the infection.

How is it best taken?

• To gain the most benefit, do not miss doses.

• Take prescription as directed, even if you are feeling better.

• Take this medicine at a similar time of day.

• Take this medicine on an empty stomach. Take 1 hour before or 2 hours after meals.

• Take this medicine with a full glass of water.

• Follow diet instructions. Certain foods and drinks taken with this medicine can cause very dangerous reactions such as sudden high blood pressure. To prevent these problems, get a list of foods to avoid from a nutritionist.

• Avoid eating aged cheeses and meats, soy sauce, soy bean including paste, Miso soup, Italian green beans (fava beans), snowpea or broad bean pods, sauerkraut, kimchee, concentrated yeast extracts (Marmite), red or white wine, and beer including alcohol-free beer.

• If medicine is stopped, follow diet for at least 2 more weeks.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Have an eye exam.

• Follow up with healthcare provider.

How should I store this medicine?

• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2005-04-07 17:16:02.0

Modified: 2010-03-09 08:29:18.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

 
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