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Rosiglitazone and Glimepiride
What is it? Overview Usage Side Effects and Warnings

Rosiglitazone and Glimepiride Overview

Written by FoundHealth.

(roh si GLI ta zone & GLYE me pye ride)

U.S. Brand Names


Pharmacologic Category

Antidiabetic Agent, Sulfonylurea; Antidiabetic Agent, Thiazolidinedione

What key warnings should I know about before taking this medicine?

• This medicine may cause or worsen heart failure. It may increase the risk of chest pain or heart attack. Talk with healthcare provider.

• Please read the medication guide.

Reasons not to take this medicine

• If you have an allergy to glimepiride, rosiglitazone or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have a sulfonamide ("sulfa") allergy, talk with healthcare provider.

• If you have any of the following conditions: Severely weakened heart, type 1 diabetes, or yellowing skin or eyes during troglitazone therapy.

• If you are breast-feeding.

How does it work?

• Rosiglitazone increases insulin activity in the body.

• Glimepiride increases insulin secretion from the pancreas and may make tissues more responsive to insulin.

How is it best taken?

• Take this medicine with the first meal of the day.

• Follow diet plan and exercise program as recommended by healthcare provider.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood sugar as directed by healthcare provider.

• Check blood work regularly. Talk with healthcare provider.

• Check weight weekly. Report a weight change to healthcare provider.

• Have a yearly eye exam and visit to the foot doctor.

How should I store this medicine?

• Store at room temperature.

• Protect from light.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2006-02-06 14:13:12.0

Modified: 2010-03-09 08:29:15.0

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