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What is it? Overview Usage Side Effects and Warnings

Sirolimus Side Effects and Warnings

Written by FoundHealth.

What are the precautions when taking this medicine?

• If you have high cholesterol, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• If you have lung disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Be careful about taking vaccinations while you are receiving this medicine.

• Do not take cyclosporine capsules (Neoral®, Gengraf®) or oral solution (Neoral®) within 4 hours of this medicine.

• Avoid grapefruit and grapefruit juice.

• Use birth control that you can trust before treatment begins, during treatment, and for 3 months after treatment ends.

• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.

What are some possible side effects of this medicine?

• High blood pressure.

• High cholesterol level.

• Risk of infection. Avoid people with infections, colds, or flu.

• Anemia and low platelet count.

• Feeling tired or weak.

• Headache.

• Belly pain.

• Diarrhea.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Swelling.

• Joint pain.

• Acne.

• Lung damage can rarely occur.

• Worsening kidney function.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Severe headache.

• Severe diarrhea.

• Unable to pass urine.

• Unusual bruising or bleeding.

• Any rash.

• No improvement in condition or feeling worse.



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