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What are the precautions when taking this medicine?
• If you have diabetes, talk with healthcare provider.
• If you have high cholesterol, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• Tell dentists, surgeons, and other healthcare providers that you use this medicine.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Do not take St John's wort with this medicine. It may make this medicine less effective.
• Avoid grapefruit and grapefruit juice.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Use birth control that you can trust before treatment begins, during treatment, and for 3 months after treatment ends.
• If you are a male and sexually active, protect your partner from pregnancy during treatment and for 3 months after treatment ends. Use birth control that you can trust.
What are some possible side effects of this medicine?
• Risk of infection. Avoid people with infections, colds, or flu.
• Anemia, low white blood cell count, and low platelet count.
• High cholesterol level.
• High blood sugar. Usually reverses when stopped.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Muscle weakness.
• Not hungry.
• Lung damage can rarely occur.
• Kidney failure can rarely occur.
• Severe allergic reactions can rarely occur.
• Bowel perforation may rarely occur.
Reasons to call healthcare provider immediately
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Difficulty breathing.
• Severe belly pain or bloody diarrhea.
• Increased trips to the bathroom, increased thirst, or weight loss.
• Severe nausea or vomiting.
• Severe diarrhea.
• Unusual bruising or bleeding.
• Skin wound that will not heal.
• Any rash.
• No improvement in condition or feeling worse.