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Vitamin B2
What is it? Overview Usage Side Effects and Warnings

Vitamin B2 Usage

Written by FoundHealth.

Therapeutic Uses

Preliminary evidence suggests that riboflavin supplements taken at high dosages may reduce the frequency of migraine headaches . 1 One very large study suggests that riboflavin at nutritional doses may be helpful for cataracts , but in this study it was combined with another B vitamin—niacin ( vitamin B 3 )—so it's hard to say which vitamin was responsible for the effect. 2 Riboflavin has also been proposed as a treatment for sickle-cell anemia , 3 HIV infection, 4 and as a performance enhancer for athletes, but there is no real evidence that it is effective for these uses.


  1. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology. 50(2):466-70.
  2. Sperduto RD, Hu TS, Milton RC, et al. The Linxian cataract studies. Two nutrition intervention trials. Arch Ophthalmol. 1993;111:1246-1253.
  3. Ajayi OA, George BO, Ipadeola T. Clinical trial of riboflavin in sickle cell disease. East Afr Med J. 70(7):418-21.
  4. Tang AM, Graham NM, Saah AJ. Effects of micronutrient intake on survival in human immunodeficiency virus type 1 infection. Am JEpidemiol. 1996;143:1244-1256.


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