Vorinostat Side Effects and Warnings

What are the precautions when taking this medicine?

• If you have had blood clots, talk with healthcare provider.

• If you have diabetes, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Feeling tired or weak.

• Diarrhea.

• Cough.

• Extra muscle activity.

• Not hungry.

• High blood sugar.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Anemia or low platelet count can rarely occur. Medicine may need to be stopped.

• Abnormal taste. This is usually reversible.

• Hair loss. Hair usually grows back when medicine is stopped.

• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Swelling.

• Headache.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Chest pain or pressure or fast heartbeat.

• Severe dizziness or passing out.

• Swelling or pain of leg or arm.

• Significant change in thinking clearly and logically.

• Swelling of legs or belly.

• Severe headache.

• Severe nausea or vomiting.

• Severe diarrhea.

• Significant weight loss.

• Unusual bruising or bleeding.

• Feeling extremely tired or weak.

• Any rash.

• No improvement in condition or feeling worse.