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Like its botanical relative true indigo ( Indigofera tinctoria), wild indigo has historically been used as a source of a deep blue dye. It was also used medicinally: the natives of North America used it as a topical treatment for non-healing wounds and infections of the mouth and throat. The root is the part used.
Combination therapies containing wild indigo, echinacea, and white cedar should be taken according to label instructions.