Zoledronic Acid Side Effects and Warnings

What are the precautions when taking this medicine?

• If you are dehydrated, talk with healthcare provider.

• If you have kidney disease, talk with healthcare provider.

• If you have malabsorption syndrome or have had part of your intestine removed, talk with healthcare provider.

• If you have had thyroid or parathyroid surgery, talk with healthcare provider.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Irritation where the shot is given.

• High or low blood pressure.

• Feeling tired or weak.

• Belly pain.

• Diarrhea.

• Headache.

• Fever.

• Swelling.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Low calcium levels.

• Anemia.

• Bone, joint, or muscle pain can rarely occur.

• Jaw bone damage can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe nausea or vomiting.

• Severe diarrhea.

• Severe jaw pain.

• Severe bone, joint, or muscle pain.

• Numbness or tingling around mouth.

• Unable to pass urine.

• Any rash.

• No improvement in condition or feeling worse.